河北医学2016，Vol.22Issue(2)：177-180,4.DOI:10.3969/j.issn.1006-6233.2016.02.001
黄芩药材中黄芩苷的提取纯化工艺优化
The Optimization of Extraction and Purification Process of the Baicalin in Scutellaria Baicalensis
摘要
Abstract
Objective:To optimize the extraction and purification methods of baicalin from scutellaria baicalensis without using acid and alkali. Method:The content of banicalin were determined by HPLC. The content of banicalin was regarded as investigation target, distilled water and 50% ethanol were used as ex-tracting solution, the banicalin was purified by AB-8 macroporous adsorption resin and then eluted with dif-ferent concentrations of ethanol. The transfer rate was investigated.Result:The optimal extraction and purifi-cation process:extracted by 50% ethanol, recouered by ethanol, eluted by 70% ethanol. Conclusion: The extraction and purification methods of baicalin from Scutellaria baicalensis without using acid and alkali re-duce the damage of baicalin and environmental pollution by acid and alkali, which is suitable for industrial-ized production.关键词
黄芩/黄芩苷/HPLC/大孔吸附树脂Key words
Scutellaria baicalensis/Baicalin/HPLC/Macroporous adsorption resin引用本文复制引用
张琳,周化更,刘沛,刘喜纲,常金花,刘翠哲..黄芩药材中黄芩苷的提取纯化工艺优化[J].河北医学,2016,22(2):177-180,4.基金项目
国家自然基金,(No.81341143) （No.81341143）
河北省高校重点学科建设项目资助.河北省高等学校科学技术研究青年基金项目,(QN20131020) （QN20131020）
