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C反应蛋白白细胞介素-6及白细胞计数在足月胎膜早破宫内感染中的意义

杨碧玉 张国琼

河北医学2016,Vol.22Issue(2):264-266,3.
河北医学2016,Vol.22Issue(2):264-266,3.DOI:10.3969/j.issn.1006-6233.2016.02.032

C反应蛋白白细胞介素-6及白细胞计数在足月胎膜早破宫内感染中的意义

Combined Detection of WBC Count, IL-6 and CRP in the Intrauterine Infection of Premature Rupture of Membranes

杨碧玉 1张国琼2

作者信息

  • 1. 四川省新津县人民医院,四川 新 津 611430
  • 2. 重庆市合川区人民医院妇产科,重庆 合川区 401520
  • 折叠

摘要

Abstract

Objective:To investigate the significance of combined detection of CRP , IL-6 and WBC count in the intrauterine infection of PROM pregnant women. Method:Retrospectively analysed 60 cases of term PROM pregnant women in our hospital, according to the film breaking time, were divided into >24h group and ≤24h group, 30 cases in each group. Another 30 cases over the same period in our hospital nor-mal full-term parturient woman were selected as the control group. CRP , IL-6 level and WBC count were detected, and its influence on PROM intrauterine infection was analyzed. Result:The levels of CRP, IL-6 and WBC in PROM were significantly higher than those in the control group, the difference was significant(P<0.05);The CRP, IL-6 level and WBC count of patients with rupture of membrane in the >24h group was higher than that in the≤24h group, and the count of the>24h group were higher than that of the≤24h group, the difference was significant (P<0.05); The levels of CRP, IL-6 and WBC were higher in the PROM pregnant women at the time of application of 24 hours, than those of 72 hours, the difference was sig-nificant (P<0.05). Conclusion: The combined detection of CRP, IL-6 and WBC has important signifi-cance for the prediction and diagnosis of early intrauterine infection of PROM in pregnant women, which pro-vides theoretical basis for clinical rational use of antibiotics.

关键词

胎膜早破/宫内感染/C反应蛋白/白细胞介素-6/白细胞

Key words

Premature rupture of membranes/Intrauterine infection/CRP/IL-6/WBC

引用本文复制引用

杨碧玉,张国琼..C反应蛋白白细胞介素-6及白细胞计数在足月胎膜早破宫内感染中的意义[J].河北医学,2016,22(2):264-266,3.

基金项目

重庆市医学科研计划项目,(编号:2013-2-233) (编号:2013-2-233)

河北医学

OACSTPCD

1006-6233

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