华西口腔医学杂志Issue(1)：73-77,5.DOI:10.7518/hxkq.2016.01.015
山羊颞下颌关节盘胶原构筑和生物力学性能研究
Collagen structure and biomechanical properties of the goat temporomandibular joint disc
摘要
Abstract
To establish objectively biomechanical criteria for temporomandibular joint disc tissue engineerings. Methods Eight temporomandibular joint discs from a four-month-old goat were separated completely. A cylindrical sample with diameter of 3 mm in the anterior, intermediate, and posterior bands was obtained, and the samples underwent pre-compression test with three cycles under a speed of 0.025 mm·s−1. With the end condition for the maximum load of less than 4.9 N and 1.5 mm compression displacement, the formal compression test was performed with the same speed. Moreover, this test obtained the stress–strain relationship and elastic modulus of each disc band. Ultrastructure and collagen fiber orientation of the district zone were observed by scanning electron microscope and polarized light microscope. Results 1) The physiological strain range of an articular disc was within 10%, and the quasilinear constitutive equation of articular disc tissues can be fitted with the polynomial function: y=ax+bx2+cx3. 2) The elastic modulus of the intermediate disc zone was the largest (P<0.05). No significant difference existed between the anterior and posterior bands (P=0.361). 3) Scanning electron microscope and polarized light microscope showed an annular disc collagen network structure, which was the internal part of the goat temporomandibular joint disc. The collagen arrangement of intermediate bands was tensely arranged anterior–posteriorly. The collagen of anterior and posterior bands went through mediolaterally with intersection of anterior-posterior branch fibersd. Conclusion Annular collagen network structure is the basis for goat temporomandibular joint disc compression resistance properties. The intermediate band demonstrated higher compression resistance performance than the anterior and posterior bands.关键词
颞下颌关节盘/拟线性本构方程/压缩实验/弹性模量/扫描电子显微镜/偏振光显微镜Key words
temporomandibular joint disc/quasi linear constitution equation/compressive testing/elastic modulus/scanning electron microscope/polarized light microscope分类
医药卫生引用本文复制引用
李燕梅,包广洁,钟妮,吕玮,张文霞,王兰兰,康宏..山羊颞下颌关节盘胶原构筑和生物力学性能研究[J].华西口腔医学杂志,2016,(1):73-77,5.基金项目
国家自然科学基金 （）
