临床肝胆病杂志Issue(1)：165-168,4.DOI:10.3969/j.issn.1001-5256.2016.01.036
HBV感染小鼠模型的研究进展
Research advances in mouse models of hepatitis B virus infection
摘要
Abstract
Hepatitis B virus (HBV)is a great threat to human health,but due to its strong species specificity,there are still no ideal animal models at present to clarify the pathogenesis of HBV infection.At present,the research on HBV infection models mainly concentrates on mice,and great progress has been achieved/made.This review focuses on the advantages and disadvantages of HBV transgenic mouse mod-el,HBV-transfected mouse model,and human-mouse chimeric liver HBV mouse model,and suggests that rational application of these models helps to clarify the pathogenesis of HBV.关键词
肝炎病毒,乙型/模型,动物/小鼠,转基因/综述Key words
hepatitis B virus/models,animal/mice,transgenic/review分类
医药卫生引用本文复制引用
王军,黄豫晓,沈燕,梁姣,刘学武,李英辉,赵亚..HBV感染小鼠模型的研究进展[J].临床肝胆病杂志,2016,(1):165-168,4.基金项目
国家自然科学基金 （）
