临床神经外科杂志2016，Vol.13Issue(1)：9-12,4.DOI:10.3969/j.issn.1672-7770.2016.01.003
经额下纵裂入路显微手术切除颅咽管瘤的研究
Study on microsur gery for craniopharyngioma through subfrontal combined interhemispheric approach
摘要
Abstract
Objective To investigate the effects of microsurgery for larger craniopharyngioma through the subfrontal combined interhemispheric approach and compare it with other approaches by surveying the recovery of patients after operation .Methods 22 cases of larger craniopharyngioma patients were operated on with the subfrontal combined interhemispheric approach andprevented from internal environment disorder by carefully taking active measures .Results 22 cases of craniopharyngioma had total resection , which had a better prognoses with the subfrontal combined interhemispheric approach .Within postoperative 2 weeks, the disturbance of electrolyte and fluid balance were even more mild compared with pterional approach .All patients'daily life were not affected after followed up for 2 years.But 3patients were treated with oral antidiuretic drugs until urine volume returned to normal after 3 months .The cortisol levels of 1 patients was still below average and hormone replacement therapy was continue taken .Conclusions Intracranial large craniopharyngioma has a severe extrusion to normal anatomy such as the hypothalamus , the stalk hypophysial .Craniopharyngioma could gain satisfactory resection with sufficient field of vision under surgical-microscope with the subfrontal combined interhemispheric approach , because the micro-structure between tumor and normal structure was completely showed .关键词
额下纵裂入路/电解质紊乱/颅咽管瘤Key words
subfrontal combined interhemispheric approach/electrolyte disturbances/crani-opharyngioma分类
医药卫生引用本文复制引用
倪洪早,范月超,陈晨,朱一硕,张芸,苗发安..经额下纵裂入路显微手术切除颅咽管瘤的研究[J].临床神经外科杂志,2016,13(1):9-12,4.基金项目
六大人才高峰(NO 2014-WSW-033) （NO 2014-WSW-033）
