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半球性癫痫手术治疗的疗效分析

代金东 王晓飞 梅珊珊 马康平 刘庆祝 杨玉成 秦广彪 谭泊静 李云林

临床神经外科杂志2016,Vol.13Issue(1):35-39,5.
临床神经外科杂志2016,Vol.13Issue(1):35-39,5.DOI:10.3969/j.issn.1672-7770.2016.01.010

半球性癫痫手术治疗的疗效分析

Analysis of effects on hemispheric epilepsy with surgical treatment

代金东 1王晓飞 1梅珊珊 1马康平 1刘庆祝 1杨玉成 1秦广彪 1谭泊静 1李云林1

作者信息

  • 1. 100080 北京市海淀医院(北京大学第三医院海淀院区)功能神经科
  • 折叠

摘要

Abstract

Object To explore the efficacy of hemispheric epilepsy by surgical treatment and evaluate patients psychosocial and cognitive function after operation .Methods The authors performed a retrospective review of 93 patients.According to the preoperative comprehensive evaluations,30 accepted performed Adams anatomical hemispherectomy , 7 accepted Rasmussen functional hemispherectomy , 3 accepted hemispherotomy ,while 24 accepted multilobe-sections.The latter 29 cases accepted multilobe-sections and corpus callosotomy .Continuous follow-up 2.5 years to 6 years and 3 months.Results According to Engel curative effect classification ,43 patients were seizure free at the termination of the study .50 patients who were not seizure free .All cases had significant reduction of seizure frequency , 24 patients achieved Engel Class Ⅱoutcome , 19 Engel Class Ⅲand 7 patients Engel Class Ⅳ.The efficacy of hemispherotomy was remarkable over time with no significant change over the postoperative follow-up period .Hemiplegia of patients were not exacerbate , and muscular tension and spasticity of the trouble side were obvious reduced .Through the systematic Physical rehabilitation and neural function rehabilitation training , Limb function is obviously improved , Higher cortical functions , Life self-care ability .Social adaptation ability to different degrees of improvement .Conclusions Cerebral hemispheric surgery is safe and feasible . Epilepsy has been effectively controlled .The verbal ability of patients with postoperative function not affected , social mental psychological condition improved markedly , the quality of life has improved significantly ,plasticity of hemispheric function is related with age of onset .

关键词

药物难治性癫痫/手术治疗/疗效分析

Key words

intractable epilepsy/surgical treatment/efficacy analysis

分类

医药卫生

引用本文复制引用

代金东,王晓飞,梅珊珊,马康平,刘庆祝,杨玉成,秦广彪,谭泊静,李云林..半球性癫痫手术治疗的疗效分析[J].临床神经外科杂志,2016,13(1):35-39,5.

临床神经外科杂志

OACSTPCD

1672-7770

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