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酵母提取物对成纤维细胞的作用及抑制黑素生成的研究

廖峰 李国光 熊丽丹 杨海延 李利

日用化学工业Issue(2):97-100,4.
日用化学工业Issue(2):97-100,4.DOI:10.13218/j.cnki.csdc.2016.02.008

酵母提取物对成纤维细胞的作用及抑制黑素生成的研究

Effect of yeast extract on fibroblasts proliferation and melanin inhibition

廖峰 1李国光 2熊丽丹 3杨海延 1李利2

作者信息

  • 1. 四川省化妆品工程技术研究中心,四川成都610041
  • 2. 四川大学华西医院化妆品评价中心,四川成都610041
  • 3. 上海辉文生物技术股份有限公司,上海201210
  • 折叠

摘要

Abstract

Via the exploration of effect of the yeast extract that originated from rice wine production (WAE)on viability of fibroblast HS68 cells as well as its action for formation of melanin by melanoma B16 cells,the safety and efficacy of the WAE were examined. The results showed that,the safety WAE mass fraction for HS68 and B16 is ≤0. 10% . As comparing with the control group,when mass fraction of WAE is 0. 10% and 0. 01%,it promotes HS68 cells proliferation to 106. 36% and 109. 33% respectively. The experiments demonstrated that under the safe concentration,WAE displays the effect of promoting proliferation of HS68 cells. WAE can inhibit 68. 32%,51. 68% and 19. 77% of melanin formation when the WAE mass fraction is 0. 10%,0. 05% and 0. 01% respectively. The experiments demonstrated that under the safety mass fraction,WAE displays the effect of inhibiting melanin formation of B16 cells. As comparing with Japanese beer yeast extract (A)and domestic beer yeast extract (B)with the same mass fraction,the safety and efficacy of WAE are superior to that of A and B.

关键词

化妆品添加剂/酵母提取物/成纤维细胞/黑素/安全性/功效性

Key words

additive of cosmetics/yeast extract/fibroblast/melanin/safety/efficacy

分类

化学化工

引用本文复制引用

廖峰,李国光,熊丽丹,杨海延,李利..酵母提取物对成纤维细胞的作用及抑制黑素生成的研究[J].日用化学工业,2016,(2):97-100,4.

基金项目

四川省科技成果转化平台建设项目 ()

日用化学工业

OA北大核心CSCDCSTPCD

1001-1803

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