日用化学工业Issue(2):97-100,4.DOI:10.13218/j.cnki.csdc.2016.02.008
酵母提取物对成纤维细胞的作用及抑制黑素生成的研究
Effect of yeast extract on fibroblasts proliferation and melanin inhibition
摘要
Abstract
Via the exploration of effect of the yeast extract that originated from rice wine production (WAE)on viability of fibroblast HS68 cells as well as its action for formation of melanin by melanoma B16 cells,the safety and efficacy of the WAE were examined. The results showed that,the safety WAE mass fraction for HS68 and B16 is ≤0. 10% . As comparing with the control group,when mass fraction of WAE is 0. 10% and 0. 01%,it promotes HS68 cells proliferation to 106. 36% and 109. 33% respectively. The experiments demonstrated that under the safe concentration,WAE displays the effect of promoting proliferation of HS68 cells. WAE can inhibit 68. 32%,51. 68% and 19. 77% of melanin formation when the WAE mass fraction is 0. 10%,0. 05% and 0. 01% respectively. The experiments demonstrated that under the safety mass fraction,WAE displays the effect of inhibiting melanin formation of B16 cells. As comparing with Japanese beer yeast extract (A)and domestic beer yeast extract (B)with the same mass fraction,the safety and efficacy of WAE are superior to that of A and B.关键词
化妆品添加剂/酵母提取物/成纤维细胞/黑素/安全性/功效性Key words
additive of cosmetics/yeast extract/fibroblast/melanin/safety/efficacy分类
化学化工引用本文复制引用
廖峰,李国光,熊丽丹,杨海延,李利..酵母提取物对成纤维细胞的作用及抑制黑素生成的研究[J].日用化学工业,2016,(2):97-100,4.基金项目
四川省科技成果转化平台建设项目 ()