陕西中医Issue(3)：370-372,3.DOI:10.3969/j.issn.1000-7369.2016.03.050
芪黄疽愈方对大鼠肢体动脉硬化闭塞症血流变的影响
The influence of Qihuang Juyu prescription on blood hemorheology in rats with arteriosclerossis obliterans
摘要
Abstract
Objective :To study the effect of Qihuang Juyu prescription on blood rheology in rats with arterio ‐sclerossis obliterans .Methods :50 Wistar rats by making rat model of ASO for high fat diet fed feeding and saphenous ar‐terial intimal injury method ,then the modeling were randomly divided into model group ,Chinese medicine group (the high ,low and middle concentration group of Qihuang Juyu prescription) ,western medicine group ,and another 10 Wistar rats were taken as the blank group .Blank group were given normal diet ,model group given high fat diet and with physio‐logical saline by gavage ,traditional Chinese medicine group given high fat diet and to the corresponding concentration of traditional Chinese medicine orally ,the western medicine group given high fat diet and cilostazol combined with alpros‐tadil .After 12 weeks ,abdominal aortic blood was taken and blood rheology measurement study of each index .Results :Compared with normal group ,the whole blood viscosity ,high and low shear index and erythrocyte aggregation index were significantly higher in the model group ,compared with the model group ,the blood rheology indexes of western medicine group and Chinese medicine group were decreased significantly .Conclusion :Qihuang Juyu prescriptionmore can effective‐ly prevent arteriosclerosis occlusive disease occurrence and development and hardening of the arteries occlusion treatment of disease plays a positive role .关键词
闭塞性动脉硬化/血流动力学/芪黄疽愈方Key words
Arteriosclerosis obliterans/Hemodynamics/Qihuang Juyu prescription分类
医药卫生引用本文复制引用
张欣,刘远,葛建立,马云龙,宋易华,李晓东..芪黄疽愈方对大鼠肢体动脉硬化闭塞症血流变的影响[J].陕西中医,2016,(3):370-372,3.基金项目
河北省科技支撑计划项目 （）
