陕西医学杂志Issue(3)：362-363,2.DOI:10.3969/j.issn.1000-7377.2016.03.045
骨髓活检病理检查在多发性骨髓瘤诊断中的应用价值
The value of bone marrow biopsy pathological examination in the diagnosis of multiple myeloma
摘要
Abstract
Objective :To understand the advantages and disadvantages of bone marrow biopsy pathologi-cal examination in the diagnosis of MM ,define the value of bone marrow biopsy pathology in the diagnosis of MM . Methods :Use bone marrow aspiration - biopsy double specimen surgery ,to get bone marrow biopsy and smears ,a-nalysis bone marrow biopsy and smears of 153 newly diagnosed MM patients ,have a comparative study on bone marrow hyperplasia degree ,myeloma cell infiltration ,proliferation models of plasma cells and myeloma cell mor-phology .Result :The hyperplasia and the sensitivity of MM diagnosis of the bone marrow biopsy ,is significantly higher than that of bone marrow smears ,the two have a significant difference ;the myeloma cell infiltration of bone marrow biopsy is higher than that of the smears ,the difference has statistically significance ;the proliferation mode of plasma cells in bone marrow biopsy are interstitial pattern ,nodular interstitial type commonly ,the myeloma cell morphology in bone marrow smears is mainly immature plasma cell type .Conclusion :Bone marrow biopsy can accu-rately reflect the plasma cells proliferation model ,compare to smears ,can have better reflection on bone marrow hy-perplasia and infiltration degree ,and have better sensitivity than smears on the diagnosis of MM ,however ,the plas-ma cells morphology of bone marrow smears is clear ,features typical ,easily identifiable .Bone marrow smears and biopsy synchronous check can improve the sensitivity and accuracy for MM diagnosis ,which has very important sig-nificance for MM early diagnosis and treatment observation .关键词
多发性骨髓瘤/病理学/骨髓检查/方法/骨髓涂片/活组织检查,细针/浆细胞Key words
Multiple myeloma/pathology/Bone marrow/examinoction/methods/Biopsy ,fine-neddle/Plasma cells分类
医药卫生引用本文复制引用
杨娣娣,韩秀蕊,李艳春,赵园,张丽洁,王九菊,魏绪仓..骨髓活检病理检查在多发性骨髓瘤诊断中的应用价值[J].陕西医学杂志,2016,(3):362-363,2.基金项目
陕西省社会发展攻关基金资助项目 （）
