现代妇产科进展2016，Vol.25Issue(2)：106-111,6.DOI:10.13283/j.cnki.xdfckjz.2016.02.007
防粘连措施预防术后盆腹腔粘连有效性及安全性的meta分析
Clinical efficacy and safety of adhesion prevention measures in preventing postoperative abdominopelvic adhesions:a Meta-analysis
摘要
Abstract
Objective:To assess the clinical effectiveness and safety of biological ad-sorbable anti adhesion membrane in preventing postoperative abdominopelvic adhesions. Meth-ods:The following databases such as PubMed、Spring、OVID、CBM、CNKI、Wanfang data were searched to collect the randomized control trails ( RCTs ) about the clinical effectiveness and safety of biological adsorbable anti adhesion membrane ( HC-CMC ) in preventing postoperative abdominopelvic adhesions. According to the inclusion and exclusion criteria to search studies, extracted data,and evaluated the methodological quality. The meta-analysis was performed using RevMan software version 5. 3. Results:Seven RCTs were included. In the aspect of validity,me-ta-analyses showed that compared with the control gruop,The incidence of adhesions have sta-tistical significance(P<0. 00001). The incidence of adhesions degree level2,level3 have statis-tical significance. The incidence of adhesions degree level 1 have no statistical significance( P=0. 82). The incidence of adhesions scope level 2,level 3 have statistical significance. The inci-dence of adhesions scope level 1 have no statistical significance ( P=0 . 1 ) . Meta-analyses showed that compared with the control gruop,the intraoperatve blood loss have statistical signifi-cance(P<0. 00001). Postoperative intestinal obstruction,abdominal abscess,the incidence of wound infection,high fever were not statistically significant. Conclusion:Application of adsorb-able anti adhesion membrane in the operation can reduce the incidence of abdominopelvic adhe-sion,reduce the degree of adhesion, reduce the scope of adhesion, reduce the intraoperatve blood loss. But the abdominal abscess,intestinal obstruction,wound infection and the incidence of postoperative adverse reaction such as high fever is similar.关键词
生物可吸收防粘连膜/盆腹腔粘连/Meta分析Key words
HA-CMC/Abdominopelvic adhesion/Meta-analysis分类
医药卫生引用本文复制引用
王晚露,马彩玲,吴强强..防粘连措施预防术后盆腹腔粘连有效性及安全性的meta分析[J].现代妇产科进展,2016,25(2):106-111,6.基金项目
国家自然科学基金资助项目(No:81160278) （No:81160278）
