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病毒性肝炎合并血小板减少症134例的临床分析

何伟 刘文丹 张小冬 秦如斋 潘春华

临床医学工程2016,Vol.23Issue(1):84-85,2.
临床医学工程2016,Vol.23Issue(1):84-85,2.DOI:10.3969/j.issn.1674-4659.2016.01.0084

病毒性肝炎合并血小板减少症134例的临床分析

Clinical Analysis of 134 Cases of Viral Hepatitis Complicated with Thrombocytopenia

何伟 1刘文丹 1张小冬 1秦如斋 1潘春华1

作者信息

  • 1. 广州医科大学附属第四医院肿瘤科, 广东广州511447
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摘要

Abstract

Objective To analyze 134 cases of viral hepatitis complicated with thrombocytopenia. Methods 134 cases of viral hepatitis treated in our hospital from July 2014 to August 2015 were selected as observation group, and 134 healthy check-ups were selected as control group. The levels ofγ-GT, ALP, AST and ALT of two groups was compared;through enzyme linked immunosorbent assay, the level of serum thrombopoietin (TPO) were detected. Flow cytometry was used to detect the expressions of PAIg, PAIgG, PAIgA and PAIgM. Results The levels ofγ-GT, ALP, AST and ALT of observation group were significantly higher than those of control group (P<0.05). The reduced level of PLT, and PLT level of observation group were significantly lower than those of control group (P<0.05). The levels of PAlg and PAlgG of observation group were significantly higher than those of control group, and the TPO level was significantly lower than that of control group (P<0.05). The levels of PAlgM and PAlgA between two groups were not significantly different (P>0.05). Conclusions The viral hepatitis complicated with thrombocytopenia is closely related with hepatic damage and mediates PAIg immune mechanism.

关键词

临床观察/血小板减少症/病毒性肝炎

Key words

Clinical observation/Thrombocytopenia/Viral hepatitis

分类

医药卫生

引用本文复制引用

何伟,刘文丹,张小冬,秦如斋,潘春华..病毒性肝炎合并血小板减少症134例的临床分析[J].临床医学工程,2016,23(1):84-85,2.

临床医学工程

1674-4659

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