肿瘤相关巨噬细胞和CCL5在胃癌中的表达及其相关性研究OA北大核心CSCDCSTPCD
Expression and correlation of tumor-associated macrophages and CCL5 in ganstric cancer
目的:研究胃癌中肿瘤相关巨噬细胞( TAM)与CCL5的表达及其相关性。方法:选择临床病理资料齐全的胃癌蜡块标本48例,癌旁组织作为对照,采用SP免疫组化法检测CD68和CCL5在胃癌组织及癌旁组织中的表达,并采用Spearman相关性统计方法对其相关性进行统计。结果:CD68和CCL5在胃癌组织中均呈阳性表达,且明显高于癌旁组织( P<0.01);CD68和CCL5与胃癌组织浸润深度、淋巴结转移情况、TNM分期情况及肿瘤分化程度均具有相关性(P…查看全部>>
Objective:To study the expression and correlation of tumor-associated macrophages(TAM) and CCL5 in ganstric cancer.Methods:48 cases patients with completed clinical and pathological data of gastric cancer paraffin block specimens were select-ed.Cancer tissues and adjacent tissues were used as control,using SP immunohistochemical method to detect CD68 and CCL5 in gastric cancer tissues and adjacent tissues,and using the Spearman correlation statistics statist…查看全部>>
丁海霞;赵连梅;单保恩
河北医科大学第四医院肿瘤研究中心,石家庄050000河北医科大学第四医院肿瘤研究中心,石家庄050000河北医科大学第四医院肿瘤研究中心,石家庄050000
医药卫生
胃癌TAMCCL5
Ganstric cancerTumor associated macrophages( TAM)CCL5
《中国免疫学杂志》 2016 (1)
74-78,5
本文为河北省自然科学基金资助项目(No.H2015206376)。
评论