中国药房2016，Vol.27Issue(3)：318-320,3.DOI:10.6039/j.issn.1001-0408.2016.03.11
我院华法林临床应用分析
Analysis of Clinical Application of Warfarin in Our Hospital
徐丙发 1林绪芳 1孔薇 1范鲁雁1
作者信息
- 1. 安徽医科大学第三附属医院/合肥市第一人民医院药学部,合肥 230061
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the clinical application of warfarin in inpatients of our hospital,and provide reference for standardized application in clinic. METHODS:Totally 267 inpatients records used warfarin in our hospital from Jan. 2013 to Jun. 2014 were investigated to retrospectively analyze the indications,dosage,international normalized ratio(INR)monitoring and bleeding complications of warfarin. RESULTS:Warfarin was mainly used for patients with deep vein thrombosis,cerebral infarc-tion,rheumatic heart disease and pulmonary embolism in our hospital;the dosage of inpatients was in the range of 0.625-6.875 mg with average daily dosage of (2.15 ± 0.72) mg;the INR lower than 1.8 accounted for 52.8%,the INR in the range of 1.8-3.0 (reaching the standard) accounted for 31.8% and INR higher than 3.0 accounted for 15.4%;incidence of adverse reactions was 5.6%,mainly subcutaneous blood spots (petechiae) and urine occult blood,and incidence of severe hemorrhage (intracerebral hemorrhage) was 0.7%. CONCLUSIONS:At present,the clinical application of warfarin is still deficient,and qualified rate of INR is still low. It's important to actively carry out medication intervention and clinical pharmaceutical care.关键词
华法林/临床应用/国际标准化比值/调查分析/药学监护Key words
Warfarin/Clinical application/International normalized ratio/Investigation and analysis/Pharmaceutical care分类
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徐丙发,林绪芳,孔薇,范鲁雁..我院华法林临床应用分析[J].中国药房,2016,27(3):318-320,3.
