中国药房2016，Vol.27Issue(3)：415-417,3.DOI:10.6039/j.issn.1001-0408.2016.03.45
复方金芩片的质量标准研究
Study on the Quality Standard of Fufang Jinqin Tablet
司席席 1孙洪胜2
作者信息
- 1. 山东中医药大学药学院,济南 250035
- 2. 山东中医药大学附属医院,济南 250011
- 折叠
摘要
Abstract
OBJECTIVE:To establish the quality standard of Fufang jinqin tablet. METHODS:TLC was conducted for the qual-itative identification of Cortex phellodendri and Lonicera japonica in the preparation. And HPLC was conducted for the content de-termination of baicalin;the column was Zorbax Eclipse XDB-C18 with mobile phase of methanol-0.2% phosphoric acid water(40:60,V/V)at a flow rate of 1.0 ml/min,the detection wavelength was 280 nm,column temperature was 35 ℃,and the injection vol-ume of 10 μl. RESULTS:C. phellodendri and L. japonica of TLC showed clear spots and good separation. The linear range of ba-icalin was 0.533-4.264 μg(r=0.999 9);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 96.95%-99.70%(RSD=1.18%,n=6). CONCLUSIONS:The standard can be used for the quality control of Fufang jinqin tablet.关键词
复方金芩片/黄芩苷/薄层色谱法/高效液相色谱法/质量标准Key words
Fufang jinqin tablet/Baicalin/TLC/HPLC/Quality standard分类
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司席席,孙洪胜..复方金芩片的质量标准研究[J].中国药房,2016,27(3):415-417,3.
