帕罗西汀联合小剂量奥氮平对抑郁症伴失眠患者睡眠进程和睡眠结构的影响OA北大核心CSTPCD
Effect of Paroxetine Combined with Low Dose of Olanzapine on Sleep Process and Architecture of Depression Patients with Insomnia
目的：探讨帕罗西汀联合小剂量奥氮平对抑郁症伴失眠患者睡眠进程和睡眠结构的影响。方法：84例抑郁症伴失眠患者随机均分为对照组和观察组。对照组患者给予帕罗西汀片20 mg，每日早晨口服1次；观察组患者在对照组治疗的基础上加用奥氮平片2.5 mg，每日睡前口服1次。观察两组患者治疗前和治疗3、6个月后的睡眠质量[匹兹堡睡眠质量指数（PSQI）]、抑郁情绪评分[汉密顿抑郁量表（HAMD）]、睡眠进程[睡眠潜伏期（SL）、觉醒次数（AT）、实际睡眠总时间（…查看全部>>
OBJECTIVE:To study the effect of paroxetine combined with low dose of olanzapine on sleep process and architec-ture of depression patients with insomnia. METHODS:84 depression patients with insomnia were randomly divided into control group and observation group. Control group was given 20 mg Paroxetine tablet,once every morning;observation group was addi-tionally given 2.5 mg Olanzapine tablet,once before going to bed. Sleep quality [Pittsburgh Sleep Quality…查看全部>>
杨冬林;刘立芬;郝英霞;栾清明
济宁市精神病防治院，山东济宁 272051济宁市精神病防治院，山东济宁 272051济宁市精神病防治院，山东济宁 272051济宁市精神病防治院，山东济宁 272051
医药卫生
帕罗西汀奥氮平抑郁症失眠睡眠进程睡眠结构
ParoxetineOlanzapineDepressionInsomniaSleep processSleep architecture
《中国药房》 2016 (6)
743-745,3
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