中国药房Issue(6)：760-762,3.DOI:10.6039/j.issn.1001-0408.2016.06.14
万古霉素致儿童中性粒细胞减少不良反应/不良事件分析
Analysis of Vancomycin-induced Neutropenia Adverse Reactions/Adverse Events in Children
季欢欢 1罗健 1宋林 1周波 1田晓颖 1贾运涛1
作者信息
- 1. 重庆医科大学附属儿童医院/儿童发育疾病研究教育部重点实验室，重庆 400014
- 折叠
摘要
Abstract
OBJECTIVE:To provide reference for vancomycin-induced neutropenia adverse reactions/adverse events in clinical diagnosis. METHODS:With a case of children with neutropenia treated by long-course and large-dose vancomycin,PubMed and CNKI were retrieved to collect related literature and the literature was analyzed. RESULTS:Neutropenia may be associated with vancomycin,based on causality criterion of adverse reaction in China. CONCLUSIONS:Vancomycin-induced neutropenia in chil-dren is most likely associated with prolonged exposure induced by infusion,vancomycin dosage should be reduced or stopped,and routine blood and plasma concentration should be closely monitored.关键词
万古霉素/中性粒细胞减少/相关性/儿童/不良反应/不良事件Key words
Vancomycin/Neutropenia/Correlation/Children/ADR/ADE分类
医药卫生引用本文复制引用
季欢欢,罗健,宋林,周波,田晓颖,贾运涛..万古霉素致儿童中性粒细胞减少不良反应/不良事件分析[J].中国药房,2016,(6):760-762,3.
