中国医学创新Issue(3)：14-17,4.DOI:10.3969/j.issn.1674-4985.2016.03.005
改良封闭负压辅助闭合技术联合干细胞移植治疗难愈合性伤口的研究
Study on the Improved Vacuum-assisted Closure Combining with SCT in the Treatment of Intractable Wounds
摘要
Abstract
Objective: To study the clinical efficacy of the improved vacuum-assisted closure and SCT in the treatment of intractable wounds.Method: In the research, 60 patients with intractable wounds in our hospital were chosen and divided into the conventional group and the research group, each group had 30 cases. The patients in the conventional group were cured by the improved vacuum-assisted closure while that of the research group were cured by the improved vacuum-assisted closure combining with SCT. The clinical efficacy, cytokine expression at different time after treatment, times of dressing change and treatment cycle of the two groups were compared. Result: The total effective rate, vascular endothelial cell after one week and two weeks of treatment, the expression rate of epidermal growth factor in the research group were higher than that in the conventional group(P<0.05). Comparing to the conventional group, the research group had earlier growth time of granulation tissue, shortertreatment cycle and fewer times of dressing change(P<0.05).Conclusion: The combination of the improved vacuum-assisted closure and SCT in the treatment of intractable wounds has significant efficacy, which can reduce the body pain of the patients, improve the quality of the patients’ life. It should be well applied by the medical institutions.关键词
难愈合性伤口/封闭负压辅助闭合技术/干细胞移植/临床疗效/治疗周期Key words
Intractable wounds/Vacuum-assisted closure/Stem cell transplantation/Clinical efficacy/Treatment cycle引用本文复制引用
陈伟锋,吴海燕,张文瑜,谢娟紫..改良封闭负压辅助闭合技术联合干细胞移植治疗难愈合性伤口的研究[J].中国医学创新,2016,(3):14-17,4.基金项目
广东省医学科学技术研究基金项目 （）
