摘要
Abstract
Objective:To investigate the influence factors of successful withdraw machine and extubation in acute exacerbation of chronic obstructive pulmonary disease(AECOPD) and serious respiratory failure patients who underwent invasive mechanical ventilation.Method:The clinical data of 100 cases of AECOPD and serious respiratory failure patients who underwent invasive mechanical ventilation in our hospital from January 2013 to June 2015 were retrospectively analyzed.Patients who successful withdrew machine and extubation were selected as the effective group,patients who were failure to withdraw machine and extubation and death were selected as the invalid group.The single factor analysis was used to analyze the influencing factors of successful withdraw machine and extubation.The independent influencing factors were given the multi-factor Logistic regression analysis. Result:The results of the single factor analysis showed that the age,HGB level before intubation tube,the WBC, NEU%,HBG,ALB,CRP levels at the time of extubation,MODS and ventilation time in the effective group were better than those in the invalid group,the differences were statistically significant(P<0.05).The results of the multi-factor Logistic regression analysis showed that the age,HGB level before intubation tube,the NEU % and ALB levels at the time of extubation,MODS and ventilation time were the independent influencing factors for successful withdraw machine and extubation(P<0.05).Conclusion:Mechanical ventilation is an effective treatment measure for AECOPD with severe respiratory failure.There are many influence factors for successful withdraw machine and extubation.Positive interventions for the influence factors of successful withdraw machine and extubation has important clinical significance.关键词
慢性阻塞性肺疾病/急性加重/呼吸衰竭/有创机械通气/成功撤机拔管/护理干预Key words
Chronic obstructive pulmonary disease/Acute exacerbation/Respiratory failure/Invasive mechanical ventilation/Successful weaning and extubation/Nursing intervention
