摘要
Abstract
ObjectiveTo investigate the curative effect of alprostadil combined with sodium nitroprusside inhalation in the treatment of neonatal persistent pulmonary hypertension. MethodsThe clinical data of 200 cases with pulmonary arterial hypertension newborn children in our hospital from May 2012 to May 2015 were retrospectively analyzed, divided in accordance with different methods in the treatment for two groups, with 100 cases in each group, all patients were given head mask pressurized oxygen, anticoagulation, strong heart, diuresis therapy, the observation group further received alprostadil and atomized inhalation of sodium nitroprusside. The clinical curative effect of two groups was observed, as well as treatment before and after arterial oxygen saturation (SaO2), pulmonary arterial systolic blood pressure (PAP), heart rate (HR), blood pressure (BP) and blood oxygen partial pressure (PaO2) and other indicators.Results The total effective rate of observation group was 57%, significantly higher than that in the control group (P>0.05), and the difference was statistically significant (P<0.05). The two groups had no significant difference (SpO2), PAP, PaO2, BP, HR, PAP, SpO2, and PaO2, and the difference was statistically significant (P<0.05). ConclusionThe alprostadil combined with sodium nitroprusside inhalation is an effective method for the treatment of neonatal pulmonary hypertension.关键词
前列地尔/雾化吸入/硝普钠/新生儿/持续肺动脉高压Key words
Alprostadil/Inhalation/Sodium nitroprusside/Neonatal/Persistent pulmonary hypertension分类
医药卫生
