中国医药科学Issue(1)：155-157,3.
小儿先天性肾积水血清Cys C、β2-MG、α1-MG含量水平及临床意义
Content level and clinical significance of serum Cys C,β2-MG,α1-MG in children with congenital hydronephrosis
摘要
Abstract
Objective To study the content level and clinical significance of serum cystatin C (Cys C),β2-microglobulin (β2-MG),α1-microglobulin (α1-MG) in children with congenital hydronephrosis.Methods 96 children with congenital hydronephrosis,who were received and surgical treated in our hospital from Februry 2014 to July 2015,were selected as the study group,were divided into mild group,moderate group,and severe group according to the severity of children disease,and were divided into preoperative group and postoperative group according to whether received surgical or not.Another 60 healthy children,who were carried out physical examination in medical examination center of our hospital at the same time,were selected as the control group.To compare the content level of serum Cys C,β2-MG,α1-MG between the two groups.ResultsThe content level of serum Cys C,β2-MG,α1-MG in study group[(1.02±0.31)mg/L,(3.83±0.93)mg/L,(25.21±5.26)mg/L] were higher than which in control group[(0.81±0.16)mg/L,(1.95±0.42)mg/L,(20.11±4.12)mg/L],which in mild group, moderate group,and severe group had increased orderly,and which in preoperative group[(0.86±0.19)mg/L,(2.02±0.45)mg/L,(22.52±4.54)mg/L] was significantly lower than which in postoperative group[(1.02±0.31)mg/L,(3.83±0.93)mg/L,(25.21±5.26)mg/L], the differences was statically significant(P<0.05).Conclusion The content level of serum Cys C,β2-MG,α1-MG in children with congenital hydronephrosis has obviously increased,is positive correlation with the severity of disease,could be significantly reduced after surgical treatment,could be the effective clinical idex on the aided diagnosis,the judgment on the hydronephrosis and severity condition.关键词
小儿肾积水/清胱抑素C/β2-微球蛋白/α1-微球蛋白Key words
Children with congenital hydronephrosis/Cys C/β2-MG/α1-MG分类
医药卫生引用本文复制引用
谭旭明,林伟卓,陆明韬..小儿先天性肾积水血清Cys C、β2-MG、α1-MG含量水平及临床意义[J].中国医药科学,2016,(1):155-157,3.基金项目
广东省东莞市科技计划项目（201410515000130）。 （）
