中国医药科学Issue(2)：159-162,4.
三阴型乳腺癌新辅助化疗的疗效观察
Effect observation of neoadjuvant chemotherapy for triple negative breast cancer
吴楚成 1陈迪 1陈淑如 1冯得财 1方勤 1彭伟强1
作者信息
- 1. 广东省惠州市中心人民医院乳腺外科，广东惠州516001
- 折叠
摘要
Abstract
Objective To investigate the curative effect of TEC regimen of neoadjuvant chemotherapy for triple negative breast cancer. Methods 118 breast cancer patients of receiving TEC regimen of neoadjuvant chemotherapy were reviewed. There were 52 patients with triple negative breast cancer and 66 patients with non-triple negative breast cancer. The curative effect and expression of Ki67 for two groups was observed. Results The rate of high expression Ki67 in the triple negative group was higher than non-triple negative group (78.9% vs.53.0%, P=0.001);for triple negative group, the patients with higher expression of Ki67 could be easier to get pCR than patients with lower expression of Ki67 (P=0.022). The pCR, CR, OPR, ORR, SD and PD in triple negative group was 28.8%, 36.5%, 51.9%, 88.5%, 9.6% and 1.9% while the rate in non-triple negative group was 7.6%, 17.3%, 47.0%, 62.1%, 34.8% and 3%; The pCR, CR, ORR and SD for two groups was significantly different (P<0.05). Conclusion The application of TEC regimen can get the higher pCR rate in the neoadjuvant chemotherapy of triple negative breast cancer. The high expression of Ki67 is often seen in the triple negative breast cancer and easier to get pCR.关键词
新辅助化疗/TEC方案/三阴型乳腺癌/Ki67Key words
Neoadjuvant chemotherapy/TEC regimen/Triple negative breast cancer/Ki67分类
医药卫生引用本文复制引用
吴楚成,陈迪,陈淑如,冯得财,方勤,彭伟强..三阴型乳腺癌新辅助化疗的疗效观察[J].中国医药科学,2016,(2):159-162,4.
