中国医药科学Issue(2)：176-179,4.
慢性阻塞性肺疾病患者凝血状态临床观察
Clinical observation of blood coagulation state of patients with chronic obstructive pulmonary disease
刘领 1吴文杰 1杨霁 1赵惠敏 1熊鑫 1李秀业 1薛兵1
作者信息
- 1. 北京市垂杨柳医院呼吸内科，北京100022
- 折叠
摘要
Abstract
Objective To observe the correlation of blood coagulation and disease condition of patients with chronic obstructive pulmonary disease (chronic obstructive pulmonary disease, COPD). Methods Differences in four projects of blood coagulation including active partial prothrombin time (APTT), prothrombin time (PT), thrombin time (TT) and fibrinogen (FBG), dimeride (D- Ⅱ ) and other indexes of patients with COPD acute exacerbation ((COPD acute exacerbation,AECOPD)who were admitted to our hospital from January 1st 2014 to December 31st 2012 and same-aged healthy people were compared. Relationship between above indexes and pulmonary function classification, CAT grouping and qi-blood analysis results of AECOPD patients was observed. Results In the AECOPD group, APTT, PT and TT were significantly reduced, FBG and D- Ⅱ were significantly increased when compared with the healthy control group(P < 0.05). With the increasing of pulmonary function grade, CAT score and worsening of qi-blood analysis, abnormality of blood coagulation and fibrinolysis index was more significant(P<0.05). Conclusion COPD patients, especially AECOPD patients have pre-thrombotic state. Abnormality of blood coagulation is related to severity of the disease.关键词
慢性阻塞性肺疾病/凝血功能/肺功能/CAT评分/血气分析Key words
Chronic obstructive pulmonary disease/Blood coagulation/Pulmonary function/CAT score/Qi-blood analysis分类
医药卫生引用本文复制引用
刘领,吴文杰,杨霁,赵惠敏,熊鑫,李秀业,薛兵..慢性阻塞性肺疾病患者凝血状态临床观察[J].中国医药科学,2016,(2):176-179,4.
