动物营养学报Issue(2)：310-318,9.DOI:10.3969/j.issn.1006-267x.2016.02.002
鸢尾素－前体基因：分子结构、表达调控和生物学功能及其与骨骼肌纤维类型转化
Irisin-Processor Gene：Molecul ar Structure, Expressive Regulation, Biological Functions and the Associations with Skeletal Muscle Fiber Types
摘要
Abstract
Irisin, as a novel myogenic factor, is produced by shear from fibronectin typeⅢdomain containing protein 5 ( FNDC5) and then secretes into blood circulation system.Irisin and its processor gene FNDC5 ex-pression plays some roles on energy metabolism, obesity, diabetes and exercise therapy.This review summa-rized the recently research progresses about irisin and its processor gene FNDC5, majorly including their struc-ture characteristics and physiological functions.Their molecular associations with skeletal muscle fiber types were discussed, combining the extracellular and intracellular signaling pathways mediating the conversion a-mong different myofiber types.Our purpose was to provide some new ideas for improving pork quality through changing muscle fiber types.关键词
鸢尾素/前体基因/过氧化物酶体增殖物激活受体γ辅激活因子/肉质性状Key words
irisin/processor gene/PGC-1α/meat quality分类
农业科技引用本文复制引用
门小明,陶新,徐子伟..鸢尾素－前体基因：分子结构、表达调控和生物学功能及其与骨骼肌纤维类型转化[J].动物营养学报,2016,(2):310-318,9.基金项目
国家自然科学基金面上项目（31172220）；国家现代农业产业技术研究体系（CARS-36）；浙江省科技厅资助项目 （）
