动物营养学报Issue(2):385-391,7.DOI:10.3969/j.issn.1006-267x.2016.02.011
神经肽 Y 的促摄食作用及其调控机制
The Orexigenic Role and Mechanism of Neuropeptide Y
摘要
Abstract
Neuropeptide Y ( NPY) is a neurotransmitter widely spread in central and peripheral nervous system for sustaining homeostasis.The prominent role for NPY is its regulation of food intake.NPY neurons are main-ly localized in arcuate nucleus ( ARC) of hypothalamus.The projection of these neurons mainly reach paraven-tricular nucleus (PVN), ventromedial nucleus (VMN), lateral hypothalamic area (LHA) and dorsomedial nucleus ( DMN) of hypothalamus forming synaptic connection and further regulate food intake.NPY receptors are Gi/Go-protein coupled receptors including Y1 to Y8 8 kinds of subtypes.Y1 receptor plays a major role in the regulation of energy metabolism.This article reviews the structure of NPY and its role of regulating food in-take in ARC, PVN, VMN, LHA and DMN providing basic material for relative research.关键词
神经肽Y/Y受体/摄食/核团Key words
neuropeptide Y/Y receptor/food intake/nuclei分类
农业科技引用本文复制引用
王国文,邵宝平,丁艳平..神经肽 Y 的促摄食作用及其调控机制[J].动物营养学报,2016,(2):385-391,7.基金项目
国家自然科学基金项目 ()