海南医学院学报Issue(8)：777-779,783,4.DOI:10.13210/j.cnki.jhmu.20160112.002
血清 CA 125、VEGF、β-HCG 在异位妊娠早期诊断及药物保守治疗预后预测中的价值
Predictive value of CA125,VEGF,β-HCG in early diagnosis of ectopic pregnancy and drug conservative treatment prognosis
摘要
Abstract
[ABSTRACT]Objective:To investigate the predictive value of antigen 125 (CA125 ),vascular endothelial growth factor (VEGF),β-human chorionic gonadotropin (β-HCG)in the early diagnosis of ectopic pregnancy and drug conservative treat-ment prognosis.Methods:A total of 125 cases of ectopic pregnancy patients (ectopic pregnancy group)and 120 cases of normal intrauterine pregnancy(control group)received and cured in Second people's Hospital of Longgang District of Shenzhen were se-lected.The levels of CA125,VEGF,β-HCG of the two groups were determinated by ELISA.Results:The levels of CA125, VEGF of ectopic pregnancy group were significantly higher than thouse of control group(P <0.05),while the level ofβ-HCG was lower than that of control group (P <0.05).The levels of CA125,VEGF of ectopic pregnancy group were below ineffec-tive group (P <0.05),and the level ofβ-HCG was higher than ineffective group (P <0.05).When serum CA125,VEGF andβ-HCG were under joint detection,the area under curve of ROC,sensitivity,specificity,positive predictive value,negative predictive value were more than thouse of single index detection.Conclusion:Serum CA125,VEGF,β-HCG detection could be used as the evaluation index of the early diagnosis of ectopic pregnancy and drug conservative treatment prognosis together with a variety of indicators joint detection to improve the accuracy of clinical diagnosis of ectopic pregnancy,which is a simple,fast detection method and worthy of promotion.关键词
血清糖类抗原 125/血管内皮生长因子/β-人绒毛膜促性腺激素/异位妊娠/临床价值Key words
Serum carbohydrate antigen 125/Vascular endothelial growth factor/β-human chorionic gonadotropin/Ectopic pregnancy/Clinical value分类
医药卫生引用本文复制引用
石华,裴少华..血清 CA 125、VEGF、β-HCG 在异位妊娠早期诊断及药物保守治疗预后预测中的价值[J].海南医学院学报,2016,(8):777-779,783,4.基金项目
深圳市龙岗区科技计划项目(201505143001079) （201505143001079）
