口腔颌面外科杂志Issue(6)：417-420,4.DOI:10.3969/j.issn.1005-4979.2015.06.005
cN0口腔鳞癌颈部Ⅱb区淋巴结的微小转移分析
Immunohistochemistry in Detection of Lymph Node Micrometastasis in Level IIb of cN0 Oral Squamous Cell Carcinoma
范靖华 1齐伟 2毛驰2
作者信息
- 1. 浙江大学医学院附属口腔医院口腔颌面外科，浙江 杭州 310006
- 2. 北京大学口腔医院口腔颌面外科，北京 100081
- 折叠
摘要
Abstract
Objective: To investigate the incidence of occult micrometastasis in level IIb associated with cN0 oral squa-mous cell carcinoma (OSCC). Methods:A total of 419 cervical lymph nodes from 94 patients were included in this study. All lymph nodes were re-examined by anti-cytokeratin (CK) immunohistochemical staining combined with semiserial sec-tions. Results: Among the 419 cervical lymph nodes, CK staining identified metastatic carcinoma in two cases, which showed carcinoma metastasis simultaneously on routine pathological examination. Among the 417 pathological negative lymph nodes, two metastases (1.0 mm×0.5 mm and 0.7 mm×0.8 mm) were detected by CK staining in only one lymph node in level IIb harboring. Conclusion:The incidence of level Ⅱb lymph nodes metastasis was very low for patients with cN0 OSCC, so it is unnecessary to dissect levelⅡb lymph nodes in patients with early cN0 OSCC.关键词
口腔鳞癌/Ⅱb区淋巴结/微小转移Key words
oral squamous cell carcinoma/level IIb lymph node/micrometastasis分类
医药卫生引用本文复制引用
范靖华,齐伟,毛驰..cN0口腔鳞癌颈部Ⅱb区淋巴结的微小转移分析[J].口腔颌面外科杂志,2015,(6):417-420,4.
