国际眼科杂志Issue(2)：335-338,4.DOI:10.3980/j.issn.1672-5123.2016.2.37
飞秒激光辅助角膜内皮移植术治疗大泡性角膜病变的疗效观察
Observation of femtosecond laser-assisted Descemet's stripping endothelial keratoplasty for bullous keratopathy
摘要
Abstract
Abstract•AIM: To evaluate the clinical effects and safety of femtosecond laser-assisted endothelial keratoplasty in bullous keratopathy.•METHODS:It was a retrospective case series study. Fifteen consecutive patients ( 16 eyes ) with bullous keratopathy at Nanjing General Hospital of Nanjing Military Command underwent Descemet's stripping endothelial keratoplasty whose donor grafts were dissected by a femtosecond laser from March 2013 to February 2014.The corneal irritation symptoms and the attachment of endothelial grafts were evaluated during the 12mo follow -up period. Clinical data of the best -corrected visual acuity, intraocular pressure, anterior segment optical coherence tomography and endothelial cell count were reviewed.•RESULTS: The surgical procedures for all the cases were successful and no intraoperative complication developed. The corneal irritation symptoms began relieving on 1d postoperatively and fully recovered in 3wk and never relapsed during the follow-up period. The grafts were well attached to the host except for one dislocation ( 6%) which was relocated and well attached afterward.Fluid leakage between the local graft-host interface occurred in three eyes ( 19%) and absorbed spontaneously in 3wk.At postoperative 1mo, the corneal epithelium became smooth and the edema of corneal stroma dissolved.The central corneal thickness thinned out from preoperative 811±137.55μm to postoperative 638± 86.51μm.During the follow-up period, acute rejection and graft endothelial decompensation was observed in one eye ( 6%) respectively. At the final follow -up, endothelial cell density was 1687±507cells/mm2.• CONCLUSION: The femtosecond laser -assisted Descemet's stripping endothelial keratoplasty is a safe and effective technique for corneal endothelial decompensation, which may yield thin individualized grafts efficiently and precisely.关键词
飞秒激光/角膜内皮移植/后弹力层撕除角膜内皮移植术/大泡性角膜病变Key words
femtosecond laser/endothelial keratoplasty/Descemet's stripping endothelial keratoplasty/bullous keratopathy引用本文复制引用
赵长霖,薛春燕,徐欢欢,朱小敏,黄振平..飞秒激光辅助角膜内皮移植术治疗大泡性角膜病变的疗效观察[J].国际眼科杂志,2016,(2):335-338,4.基金项目
国家自然科学基金青年基金项目（No．81200676）@@@@National Natural Science Foundation of China （）
