现代检验医学杂志Issue(1)：92-95,4.DOI:10.3969/j.issn.1671-7414.2016.01.027
女性 HPV 感染人群发生 HIV 感染风险的荟萃分析
Human Papillomavirus Infection and Increased Risk of HIV Acquisition:A Meta-analysis of Case-control Studies
摘要
Abstract
Objective To evaluate the impact of human papillomavirus(HPV)infection on the risk of HIV acquisition in the female group.Methods Searched PubMed,EMbase,Coehrane Library,CNKI,wanfang database and Chinese Biomedical Lit-erature Database etc for articles about HIV-acquisition in HPV infected female patients.The quality of the literature were e-valuated according to standards of inclusion and exclusion.Data was extracted and methodologically quality evaluated by two independent investigators.Meta-analysis was accomplished using RevMan4.2 software.Results 6 articles were included,all of them were randomized controlled trials,a total of 9 606 cases studied.HIV infection risk was doubled in women with any HPV infection(OR= 2.02,95% CI:1.48 ~ 2.77),demonstrating High-risk HPV-positive (OR= 2.50,95% CI:1.73 ~3.61)and low-risk HPV-positive (OR=2.10,95% CI:1.48~2.96)respectively.Funnel plot analysis revealed no signifi-cant publication bias on HPV genotypes.Conclusion The analysis of selected research suggests the risk of HIV infection was increased in HPV-positive women.HPV vaccine may have some preventive effect on HIV infection.关键词
人类乳头状瘤病毒/人类免疫缺陷病毒/女性人群/感染风险/荟萃分析Key words
HPV/HIV/female population/the risk of infection/meta analysis分类
医药卫生引用本文复制引用
薛渊,徐虹,沈俐..女性 HPV 感染人群发生 HIV 感染风险的荟萃分析[J].现代检验医学杂志,2016,(1):92-95,4.基金项目
镇江市社会发展项目（SH2015083），镇江市卫生科技重点项目（SH2013096）。 （）
