新医学Issue(1):7-11,5.DOI:10.3969/j.issn.0253-9802.2016.01.002
微小 RNA 与肿瘤微环境
MicroRNAs and tumor microenvironment
摘要
Abstract
MicroRNAs (miRNAs)are a class of small non-coding RNAs which regulate the inci-dence,metastasis and invasion of malignant tumors.MiRNAs are not only expressed in different tumor cells, but also in tumor microenvironment.Along with deeper exploration of tumor microenvironment,the role of miR-NAs in tumor microenvironment has been gradually identified.Tumor microenvironment consists of extracellular matrix and stromal cells,which is involved in tumor growth,metastasis and angiogenesis.MiRNAs participate in all these events.Understanding the miRNAs and tumor microenvironment contributes to identifying the path-ological and physiological mechanisms of tumor occurrence.In this review,relevant studies about the role of miRNAs in tumor microenvironment were summarized.关键词
微小RNA/肿瘤微环境/免疫细胞Key words
MicroRNAs/Tumor microenvironment/Immunocyte引用本文复制引用
葛曙雄,王涌..微小 RNA 与肿瘤微环境[J].新医学,2016,(1):7-11,5.基金项目
宁波市社会发展重大择优委托科技攻关项目 ()