云南化工Issue(1)：19-23,5.DOI:10.3969/j.issn.1004-275X.2016.01.005
γ－环糊精对槲皮素和扁桃酸的包结
Study on Inclusion of γ-Cyclodextrin to Sophretin and Mandelic Acid
杨李霞 1魏静 1张晓梅1
作者信息
- 1. 安徽理工大学 化工学院，安徽 淮南 232001
- 折叠
摘要
Abstract
The paper reported the inclusion of γ-cyclodextrin(γ-CD)to sophretin and DL -man-delic acid using γ-CD as a host molecule.Two complexes of γ-CD -sophretin and γ-CD -mandelic acid were successfully synthesized via liquid -liquid inclusion reaction,and their structures were character-ized by IR and 1H NMR.Results from 1H NMR showed that molar ratios on γ-CD -sophretin and γ-CD -mandelic acid (CD∶host)were 1∶1 and 2∶3,respectively.At 25 ℃,results from the study on phase solubility of sophretin in γ-CD confirmed the molar ratio of γ-CD to sophretin to be 1∶1,and the inclusion equilibrium constant of γ-CD to sophretin 574 L·moL -1 ;then,the solubility of sophretin in γ-CD reached 1.33mg·mL -1 .Study on specific rotation of γ-CD -mandelic acid exhibited that there was no enantioselective when γ-CD formed complex with D or L -mandelic acid.关键词
γ-环糊精/槲皮素/DL -扁桃酸/包结Key words
γ-cyclodextrin/Sophretin/DL -mandelic acid/inclusion分类
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杨李霞,魏静,张晓梅..γ－环糊精对槲皮素和扁桃酸的包结[J].云南化工,2016,(1):19-23,5.
