摘要
Abstract
Objective:To investigate the pathogenesis,clinical pathological characteristics,diagnosis,treatment and prognosis on patients with pleomorphic xanthoastrocytoma.Methods:5 patients with PXA were selcted,then they were given imaging and immunohistochemistry examination.Results: MRI showed signal shadow of 1.0 cm in diameter in the left hippocampal patchy appear abnormal.Vascular lesion area can be observed in patients with weeks lymphocyte infiltration, but vascular endothelial cell proliferation, pathological karyokinesis and necrosis were not observed.The immunohistochemical staining showed that CD163,NF, EMA and NeuN were negative.Conclusion:PXA is a rare disease of pathogenic star cell tumor.If the surgery can resection it completely,the prognosis is good,but the prognosis on primary PXA with interstitial features and malignant transformation of PXA and other high grade gliomas are generally poor.关键词
多形性黄色星形细胞瘤/临床病理分析/免疫组化Key words
Pleomorphic xanthoastrocytoma/Clinical pathological analysis/Immune group