川北医学院学报2016，Vol.31Issue(1)：42-45,4.DOI:10.3969/j.issn.1005-3697.2016.01.12
动态动脉硬化指数与老年原发性高血压病患者左心室肥厚及尿微量白蛋白的关系研究
Association study between ambulatory arterial stiffness index and left ven-tricular hypertrophy,as well as early signs of renal damage in elder pa-tients with primary hypertension
摘要
Abstract
Objective:To investigate the relationship between ambulatory arterial stiffness index (AASI)derived from blood pressure monitoring and left ventricular hypertrophy,as well as early signs of renal damage in elder patients with primary hypertension. Methods:137 primary hypertensive outpatients were divided into two groups according to their AASI values:normal AASI group (AASI≤0.5 1 ,n =76)and high AASI group (AASI >0.5 1 ,n =61 ).The urinary micro albumin uria,glomerular filt ration rates (GFR),left ventricular mass index were measured and compared.The linear regression and multiple Logistic regressions were carried between AASI and micro albumin uria,left ventricular mass index.Results:Compared with those in the normal AASI group,the patient s in high AASI group showed a higher level of urinary microalbuminuria (P =0.007)and left ventricular mass index (P <0.001 ).As AASI increas-ing,the level of urinary microalbumin uria(β=0.761 ,P =0.001 )and left ventricular mass index were also increasing(β=0.466,P =0.004).After adjusting the potentially confounding variables,the odd ratio (OR)of AASI to left ventricular hypertrophy was 1.96 (95%CI =1.67-3.98,P =0.003),to renal damage was 2.28 (95%CI =1.76-4.44,P =0.008).Conclusion:AASI is an independ-ent risk factor for left ventricular hypertrophy and early signs of renal damage in elder patients with primary hypertension.关键词
老年人群/高血压病/动态动脉硬化指数(AASI)/左心室肥大/肾损害Key words
Elders/Hypertension/Ambulatory arterial stiffness index (AASI)/Left ventricular hypertrophy/Renal damage分类
医药卫生引用本文复制引用
唐杨,王梁谦..动态动脉硬化指数与老年原发性高血压病患者左心室肥厚及尿微量白蛋白的关系研究[J].川北医学院学报,2016,31(1):42-45,4.基金项目
重庆市巴南区科委课题2010 （）
