川北医学院学报2016，Vol.31Issue(1)：58-62,5.DOI:10.3969/j.issn.1005-3697.2016.01.16
机械通气患者不同营养方式对感染及免疫功能的影响研究
Study of different nutritional modes on the effect of infection and immune function of patients with mechanical ventilation
葸英博 1李建华 1彭冲 1刘颖 1刘瑞芳 1程青虹1
作者信息
- 1. 新疆石河子大学第一附属医院重症医学二科，新疆 石河子 832008
- 折叠
摘要
Abstract
Objective:To discuss different nutritional modes on the effect of immune function of patients with ICU mechanical ventilation.Methods:1 18 cases of patients with mechanical ventilation hospitalized from October 2014 to October 2015 in Department of ICU of our hospital who were selected,according to the different nutritional methods,they were divided into 38 cases of parenteral nu-trition group (PN),41 cases of early enteral nutrition (EEN)group,39 cases of early enteral nutrition group (PEEN)with probiotics, Nutritional support treatment time >14 d,and the infection status and immune indexes of three groups were recorded.Infection site, sputum culture of bacterial species,prognosis,ICU hospital days,mechanical ventilation days and mechanical ventilation probability of two weeks of patients of three groups were compared.Results:After 14 d of nutritional treatment,the level of white blood cells of pa-tients with PEEN group was lower than that of group EEN and group PN (P <0.05);After seventh,14th day of nutritional treatment, patients with C reactive protein (CRP)and calcitonin (PCT)levels of PEEN group were lower than those of the EEN group and PN group (P <0.05);There was no significant difference in the percentage of neutrophils of 3 groups (P >0.05);Nutritional treatment of PEEN at the fourteenth day,IgA,IgG,IgM levels of patients of EEN group were higher than those of the PN group (P <0.05);And pa-tients of PEEN group were more significant than patients of EEN group (P <0.05);Nutrition at 7 th day,the 14th day,The percentage of lymphocytes of PN group was significantly lower than that of group EEN and group PEEN patients (P <0.05 );The total infection rates of patients of group EEN and group PEEN were lower than that of group PN;There was no statistically significant difference in spu-tum culture of patients between three groups,(P >0.05).Conclusion:Enteral nutrition of adding probiotics of patients with mechanical ventilation in improving immune function,and reducing the incidence of infection has a certain positive significance.关键词
机械通气/肠内营养/肠外营养/益生菌/感染/免疫Key words
Mechanical ventilation/Enteral nutrition/Parenteral nutrition/Probiotics/Infection/Immunity分类
医药卫生引用本文复制引用
葸英博,李建华,彭冲,刘颖,刘瑞芳,程青虹..机械通气患者不同营养方式对感染及免疫功能的影响研究[J].川北医学院学报,2016,31(1):58-62,5.
