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谷氨酰胺辅助肠内营养、肠外营养改善低出生体重儿喂养不耐受的临床研究

蔡晓东 陈春红 李炎芳

海南医学院学报2016,Vol.22Issue(9):864-868,5.
海南医学院学报2016,Vol.22Issue(9):864-868,5.DOI:10.13210/j.cnki.jhmu.20160125.021

谷氨酰胺辅助肠内营养、肠外营养改善低出生体重儿喂养不耐受的临床研究

Effect of glutamine with auxil iary enteral and parenteral nutrition on feeding intolerance of low birth weight infants

蔡晓东 1陈春红 2李炎芳1

作者信息

  • 1. 中山市陈星海医院 新生儿科,广东 中山 528415
  • 2. 中山市陈星海医院 药剂科,广东 中山 528415
  • 折叠

摘要

Abstract

Objective:To analyze effect of glutamine with auxiliary enteral and parenteral nutrition on feeding intoler-ance of low birth weight infants.Methods:A total of 40 low birth weight infants admitted from May 2013 to June 201 5 were se-lected,and were divided into two groups by half according to nutrition invention,observation group and control group.Infants in control group received enteral and parenteral nutrition,and infants in observation group received glutamine with auxiliary en-teral and parenteral nutrition.Growth and development indexes,nutrition status,calcium,phosphorus,gastrin,motilin,mu-cosa barrier,immune function,etc were observed and compared.Results:After intervention,Leptin,GH,IGF-Ⅰ and Adi-ponectin were significantly higher,and Cor was significantly lower in observation group (P <0.05).TSF,AMC,TP,ALB,&nbsp;calcium and phosphorus were significantly higher,and ALP was significantly lower in observation group (P <0.05).CD3 + T, CD4 + T and CD4 +/ CD8 + were significantly higher,and D-lactic acid,blood ammonia were significantly lower in observation group (P <0.05).Conclusions:Glutamine with auxiliary enteral and parenteral nutrition can improve feeding intolerance of low birth weight infants,and promote nutrition status,growth and development.

关键词

低出生体重儿/喂养不耐受/谷氨酰胺/肠内营养/肠外营养

Key words

Feeding intolerance/Low birth weight infants/Glutamine/Eenteral nutrition/Parenteral nutrition

分类

医药卫生

引用本文复制引用

蔡晓东,陈春红,李炎芳..谷氨酰胺辅助肠内营养、肠外营养改善低出生体重儿喂养不耐受的临床研究[J].海南医学院学报,2016,22(9):864-868,5.

基金项目

广东省中山市医学科研项目(2015A020092)[Foundation Project]:It is supported by Medical Science Research Project of Zhongshan (2015A020092).Author:CAI Xiao-dong (1980-),Male ,Jingmen,At-tending Physician,M.B.,Tel:0760-22287701、13420264697,Email:c 13420264697@163.com. (2015A020092)

海南医学院学报

OACSTPCD

1007-1237

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