海南医学院学报2016，Vol.22Issue(9)：876-878,3.DOI:10.13210/j.cnki.jhmu.20160125.052
灯盏花素辅助治疗对重症急性胰腺炎患者炎症因子、免疫功能和血液流变学的影响
Effect of adjuvant therapy with breviscapine on inflammatory factors,immune function and hemorheology in patients with severe acute pancreatitis
摘要
Abstract
Objective:To investigate the effect of adjuvant therapy with breviscapine on inflammatory factors,immune function and hemorheology in patients with severe acute pancreatitis.Methods:A total of 86 severe acute pancreatitis patients were divided into observation group (43 cases)and control group (43 cases).The two groups were given the arterial perfusion of octretide and the observation group was additionally given continuously arterial perfusion of breviscapine.Levels of inflam-matory factors,immune function and hemorheology were tested and compared.Results:The two groups inflammatory factors (hs-CRP,IL-6,TNF-α)levels were decreased significantly after treatment,and the observation group decreased more than that of the control group with significantly(P <0.05);The two groups the percenrage of CD4 and CD4 /CD8 were increased signifi-cantly after treatment,and the observation group increased more than that of the control group with significantly (P <0.05), there was no significant difference in the percenrage of CD8;The two groups hemorheology (blood high shear viscosity,plasma viscosity,platelet adhesion rate,thrombus length)levels were decreased significantly after treatment,and the observation group decreased more than that of the control group (P <0.05).Conclusion:Adjuvant therapy with breviscapine can obviously reduce inflammation,and improve immune function and hemorheology.关键词
重症急性胰腺炎/灯盏花素/炎症因子/免疫功能/血液流变学Key words
Breviscapine/Severe acute pancreatitis/Inflammatory factors/Immune function/Hemorheology分类
医药卫生引用本文复制引用
李抗利,王林,王超,朱卫东..灯盏花素辅助治疗对重症急性胰腺炎患者炎症因子、免疫功能和血液流变学的影响[J].海南医学院学报,2016,22(9):876-878,3.基金项目
陕西省自然科学基金资助项目(2013C998)[Foundation Project]:It is supported by Natural Science Foundation of Shaanxi Province (No ．2013C998)． （2013C998）
