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骨相关细胞因子在骨生长和重塑中的作用研究进展

季丰琨 李浩宇 彭瑞云

军事医学2016,Vol.40Issue(2):150-153,4.
军事医学2016,Vol.40Issue(2):150-153,4.DOI:10.7644/j.issn.1674-9960.2016.02.018

骨相关细胞因子在骨生长和重塑中的作用研究进展

Progress in roles of cytokines in bone formation and remodeling

季丰琨 1李浩宇 1彭瑞云2

作者信息

  • 1. 解放军总医院小儿外科,北京 100853
  • 2. 军事医学科学院放射与辐射医学研究所,北京 100850
  • 折叠

摘要

Abstract

Bone growth factors play an important role in the process of bone metabolism and perform a variety of physio -logical functions such as regulating bone growth , differentiation and remodeling .Meanwhile , these cytokines are associated with orthopedic disorder and therapy .The curative effect of the overturned sartorius iliac flap in repair of acetabular defect in developmental dysplasia of the hip proves to be good , but mechanism between the overturned flap and the surrounding bone tissue is unclear .This review briefly summarizes the functions and applications of several major cytokines in bone for -mation and remodeling , which may provide new ideas and methods for illuminating the mechanism of these cytokines during the repair of the acetabular defect .

关键词

细胞因子/骨生长/骨重塑/骨疾病,发育性/骨关节炎,髋/骨形态发生蛋白质类/转化生长因子β/成纤维细胞生长因子

Key words

cytokines/bone formation/bone remodeling/bone diseases/developmental/osteoarthritis/hip/bone mor-phogenetic protein/transforming growth factor beta/fibroblast growth factors

分类

医药卫生

引用本文复制引用

季丰琨,李浩宇,彭瑞云..骨相关细胞因子在骨生长和重塑中的作用研究进展[J].军事医学,2016,40(2):150-153,4.

军事医学

OA北大核心CSCDCSTPCD

1674-9960

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