山西中医学院学报2016,Vol.17Issue(1):16-18,3.
不同灸法对免疫抑制兔T细胞亚群、NK细胞、B细胞的影响
Effect of different moxibustion on T cell subsets,NK cells and B cells in immunosuppressive rabbits
摘要
Abstract
Objective:To observe the effect of different moxibustion on T cell subsets,NK cells and B cells in immunosuppressive rabbits induced by cyclophosphamide. Methods:50 rabbits were randomly divided into blank group, model group,cake-separated moxibustion group,moxibustion group,counterfeit moxibustion group with 10 in each group.In addition to the blank group,the other groups were injected with cyclophosphamide(60 mg/kg)for sequential 7 days to make immunosuppression model.Cake-separated moxibustion group,moxibustion group and counterfeit moxibustion group were given moxibustion 10 times respectively once every other day.Venous blood was taken from the next day after treatment and CD3+,CD4+,CD8+,NK cells,B cells of serum were tested by ELISA. Results:Compared with blank group,CD3+ was significantly decreased(P<0.01)and CD8+was apparently increased(P<0.01)in model group.Compared with model group, CD3+was significantly increased (P<0.01)and CD8+was apparently decreased (P<0.01). in cake-separated moxibustion group the difference in CD3+,CD4+,CD8+,NK cells,B cells between moxibustion group and counterfeit moxibustion group was not statistical significance. Conclusions:Cake-separated moxibustion can effectively regulate CD3+,CD8+ level induced by cyclophosphamide.关键词
环磷酰胺/免疫抑制/隔药饼灸/T细胞亚群/NK细胞/B细胞Key words
cyclophosphamide/immunosuppression/cake-separated moxibustion/T cell subsets/NK cells/B cells分类
医药卫生引用本文复制引用
单增天,吴爱花,田岳凤,李雷勇,王军..不同灸法对免疫抑制兔T细胞亚群、NK细胞、B细胞的影响[J].山西中医学院学报,2016,17(1):16-18,3.基金项目
国家自然科学基金面上项目 ()