现代妇产科进展2016，Vol.25Issue(1)：29-33,5.DOI:10.13283/j.cnki.xdfckjz.2016.01.007
静脉导管、脐静脉和脐动脉及大脑中动脉血流检测对子痫前期胎儿预后分析
The blood flow detection of ductus venosus,umbilical vein,umbilical artery and middle ;cerebral artery and prognosis analysis of preeclampsia fetus
摘要
Abstract
Objective:To investigate the blood flow detection of ductus venosus( DV) , umbilical vein( UV) ,umbilical artery( UA) and middle cerebral artery( MCA) in preeclampsia fetus(PE) and perinatals prognosis analysis. Methods:Blood flow parameters of DV,UV,UA and MCA in preeclampsia fetus and normal fetus of corresponding gestational age were assessed and compared by color Doppler ultrasound instrument,and the relation between the blood flow parameters and poor perinatal outcomes were analyzed. Results:DV, UV values of 28 ~31 weeks+6 and 36 weeks-before delivery severe preeclampsia fetus were significantly higher than that of normal and mild preeclampsia fetus(P<0. 05),and there were no significant differences between mild preeclampsia group and the control group ( P>0 . 05 ) . DV blood flow parameters including preload index( PLI)、peak flow velocity( PVIV)、pulsed index( PIV) and venous cath-eter blood flow/umbilical venous blood flow ( Qdv/Quv) in 32~35+6 weeks preeclampsia fetus all tended to increase with the severity of preeclampsia ( P<0 . 05 ) . UA values of 28 weeks~before delivery severe preeclampsia fetus were significantly higher than that of normal and mild preeclampsia fetus(P<0. 05). UA blood flow parameters including resistance index(RI),pulsa-tility index( PI) and S/D ratio between mild preeclampsia group and the control group had no obvious difference(P>0. 05). The differences of MCA blood flow parameters including RI,PI and S/D between 28 weeks-36 weeks preeclampsia group and normal group were statistically significant(P<0. 05). There was a negative correlation between DV、UV、UA blood flow param-eters in preeclampsia fetus and the birth weight of the newborns,Apgar scores、umbilical arterial blood oxygen saturation、umbilical venous PH. DV blood flow parameters including PVIV、PIV、Qdv/Quv,UA blood flow parameters including PI、S/D and MCA blood flow parameters RI had a certain relationship with birth outcomes ( P<0 . 05 ) . Conclusion:Preeclampsia fetal DV、UV changes in blood flow spectrum as indicators for determining the fetal status can be used to pre-dict the pregnancy outcomes. If we combine DV、UV and UA、MCA changes in blood flow spec-trum,the fetal status will be assessed accurately.关键词
静脉导管/脐动脉/大脑中动脉/出生结局/子痫前期Key words
Ductus venosus/Umbilical artery/Middle cerebral artery/Birth outcome/Preeclampsia分类
医药卫生引用本文复制引用
李建华,刘姿,吴曙粤,谢敏,林珏瑛..静脉导管、脐静脉和脐动脉及大脑中动脉血流检测对子痫前期胎儿预后分析[J].现代妇产科进展,2016,25(1):29-33,5.基金项目
广西南宁市科学研究与技术开发计划项目(No:20123133) （No:20123133）
广西壮族自治区卫生厅自筹经费科研课题(No:Z2012633) （No:Z2012633）
