中国全科医学2016，Vol.19Issue(8)：941-945,5.DOI:10.3969/j.issn.1007-9572.2016.08.016
肠道支架置入术与急诊手术治疗急性梗阻性结直肠癌疗效的Meta分析
Curative Effect on Acute Obstructive Colorectal Cancer by Stent Implantation in Intestinal Tract and Emergency Operation：A Meta Analysis
摘要
Abstract
Objective To systematically analyze the control study about curative effect on acute obstructive colorectal cancer by stent implantation in intestinal tract and emergency operation and evaluate the curative effect and safety of the two treatment methods.Methods Literature of randomized control trial about the treatment of acute obstructive colorectal cancer by stent implantation in intestinal tract and emergency operation were retrieved in Cochrane library, PubMed, EMBase, Chinese Biological and Medical Database ( CBM) and Wanfang Database; the quality of the selected literature was assessed.Mortality rate, permanent colostomy rate, enteroanastomosis success rate and complication rate were observed; meta analysis was conducted on the literature by RevMan 5.0.Results A total of 10 clinic randomized control trials were included in the study.The two therapies were significantly different in permanent colostomy rate 〔OR=0.37, 95%CI (0.21, 0.67), P=0.000 9〕, enteroanastomosis success rate 〔OR =2.51, 95%CI (1.54, 4.10) , P=0.000 2〕 and complication rate 〔OR =0.14, 95%CI (0.08, 0.27), P<0.000 01〕;but the two therapies were not significantly different in mortality rate 〔OR=1.10, 95%CI (0.52, 2.31), P =0.80〕.Conclusion Compared with emergency operation, the treatment of acute obstructive colorectal cancer by stent implantation in intestinal tract is more effective, safer and more reliable; permanent colostomy rate and complication rate are much lower, and enteroanastomosis success rate is significantly higher;but the effect on mortality rate shows no significant difference between the two methods.关键词
结直肠肿瘤/肠梗阻/支架/手术/Meta分析Key words
Colorectal neoplasms/Intestinal obstruction/Stent/Surgery/Meta analysis分类
医药卫生引用本文复制引用
石磊,赵伟,周宇,陈平,房晓..肠道支架置入术与急诊手术治疗急性梗阻性结直肠癌疗效的Meta分析[J].中国全科医学,2016,19(8):941-945,5.基金项目
江苏省高校自然科学基金青年科研基金(BK20140497） （）
