中国现代医学杂志2016，Vol.26Issue(4)：85-87,3.DOI:10.3969/j.issn.1005-8982.2016.04.018
肝硬化患者血清钙磷及钙调节激素的检测及意义
Significance of detecting serum calcium, serum phosphorus and calcium-regulating hormones in patients with hepatic cirrhosis
王瑜1
作者信息
- 1. 河南科技大学附属安阳市第五人民医院 检验科，河南 安阳 455000
- 折叠
摘要
Abstract
Objective To evaluate clinical significance of detecting serum calcium, serum phosphorus and calcium-regulating hormones, including parathyroid hormone (PTH), calcitonin (CT) and 25-hydroxyvitamin D3 [25-(OH)D3] in patients with hepatic cirrhosis. Methods We collected serum samples of 83 patients with hepatic cirrhosis and 66 normal people. Serum calcium was detected by Arsenazo Ⅲ colorimetric method and serum phosphorus by molybdophosphate photometric method; Electrochemiluminescence method was used to detect parathyroid hormone, calcitonin and 25-hydroxyvitamin D3. Results In Child-pugh class C patients, serum calcium levels was significantly lower than in control group and in class A and B patients ( <0.05). Serum phosphorus level was no significantly different in the four groups. Child-pugh class C patients had significantly lower 25-(OH) D3 (P< 0.01) and CT ( <0.05) level, but higher PTH ( <0.01) level compared with control group and with class A and B. Conclusions In patients with hepatic cirrhosis, there were disturbances of serum calcium and calcium-regulating hormone, which deteriorate with the disease development. It is helpful for evaluating the degree of hepatic injury to monitor the levels of serum calcium and calcium-regulating hormones in patients with hepatic cirrhosis.关键词
肝硬化/甲状旁腺激素/降钙素/25-羟维生素D3Key words
hepatic cirrhosis/parathyroid hormone/calcitonin/25-hydroxy vitamin D3分类
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王瑜..肝硬化患者血清钙磷及钙调节激素的检测及意义[J].中国现代医学杂志,2016,26(4):85-87,3.
