中国现代医学杂志2016，Vol.26Issue(5)：17-21,5.DOI:10.3969/j.issn.1005-8982.2016.05.004
香菜挥发油体外抑制Saos-2细胞生长与迁移
Coriander volatile oil inhibits growth and migration of Saos-2 cells in vitro
摘要
Abstract
Objective To extract coriander volatile oil and investigate its effects on growth and migration of human Saos-2 cells . Methods Ultrasound-assisted ethanol extraction was used to prepare coriander volatile oil. MTT assay was used to determine the growth inhibion of Saos-2 cells by volatile oil. Cell migra-tion was examined using Boyden chamber assay. Expression of 21 1/ 1, 27 1, 23 1 and 100 4 were examined by real-time PCR. Results The results showed that the yield of coriander volatile oil was 0.424% using ultrasound-assisted ethanol extraction. Coriander volatile oil inhibited the growth and migra-tion of Saos-2 cells, along with the decrease in the expression levels of 21 1/ 1, 27 1 and 100 4. Conclusions Coriander volatile oil can inhibit Saos-2 cell growth and migration in vitro, which may involve 21 1/ 1, 27 1 and 100 4.关键词
香菜挥发油/抗肿瘤/21Key words
coriander volatile oil/anti-tumour/211/1/271/1004分类
医药卫生引用本文复制引用
赖家玲,付文垚,何欣,肖川云,曹俊..香菜挥发油体外抑制Saos-2细胞生长与迁移[J].中国现代医学杂志,2016,26(5):17-21,5.基金项目
江西省卫生厅科技计划项目（No20157101）；江西省教育厅科学技术研究项目 （）
