中国现代医学杂志2016，Vol.26Issue(5)：101-104,4.DOI:10.3969/j.issn.1005-8982.2016.05.022
益生菌对化脓性扁桃腺炎治疗后发生抗生素相关性腹泻的影响
Effect of probiotic micro-organisms on antibiotic-associated diarrhoea in children with suppurative tonsillitis
甄兴刚 1千海琴 2朱永杰 1陈晓轶1
作者信息
- 1. 河南省郑州市儿童医院急诊科，河南 郑州 450053
- 2. 河南省郑州市儿童医院心电图室，河南 郑州 450053
- 折叠
摘要
Abstract
Objetive To evaluate the efficacy of live and powder in preventing antibiotic-associated diarrhea (AAD) in children with suppurative tonsillitis. Methods In this ran-domized and placebo-controlled trial in Children`s Hospital of Zhengzhou City, 537 children with suppurative tonsillitis aged from 6 months to 15 years were enrolled. Among them 353 children completed the study and were randomly divided into two groups. and powder was given daily to 197 children in the treatment group during the antibiotic treatment, while 156 children in the control group received antibiotics as a routine treatment for suppurative tonsillitis. The stool frequency and consistency were observed and recorded. Results Children in the two groups were similar in age distribution, sex and anti-biotics used. The incidence of AAD was higher in the control group (23.08%) than in the treatment group (11.17%, <0.01). And ADD occurred at a later time in the treatment group than in the control group. No related adverse reactions were found in the treatment group. Conclusions Live and combined powder can effectively reduce the risk of AAD in children with suppurative tonsillitis without occurrence of related adverse reactions.关键词
化脓性扁桃体炎/抗生素相关性腹泻/益生菌/预防Key words
suppurative tonsillitis/antibiotic-associated diarrhea/probiotics/prevention分类
医药卫生引用本文复制引用
甄兴刚,千海琴,朱永杰,陈晓轶..益生菌对化脓性扁桃腺炎治疗后发生抗生素相关性腹泻的影响[J].中国现代医学杂志,2016,26(5):101-104,4.
