中国真菌学杂志2016,Vol.11Issue(1):20-23,27,5.
肺部 CT 联合血清半乳甘露聚糖实验在白血病并发侵袭性肺曲霉菌病诊断及疗效评价中的应用
The diagnosis and therapeutic evaluation of invasive pulmonary aspergillosis in leukemia patients using CT combined with galactomannan test
李明 1李功杰 1周娟 1盛复庚 1乔鹏岗1
作者信息
- 1. 解放军 307 医院放射科,北京 100071
- 折叠
摘要
Abstract
Objective To investigate the role of chest CT image combine serum galactomannan (GM)test as predictors of therapeutic effect in leukemia patients with invasive pulmonary aspergillosis (IPA).Methods In this retrospective study from Jan 2010 to Dec 2012,we analyzed both of chest CT image and GM test in 25 patients classified as "clinical diagnosis" IPA. Result Chest CT image had four kinds of manifestations:nodules with halo sign (1 7 cases),wedge-shaped consolidation (3 cases),diffuse lesser tubercle (4 cases)and scattered patchy shadows with satellite lesions (1 case).Antifungal treatment was effectivein 1 5 cases with GM index being down to normal at the same time.In 8 cases in progress,GM index raised according-ly;when new antifungal therapy was accepted and worked well,the GM index was lower down.In 2 cases of inflammation out of control,GM index was positive constantly.Conclusion Chest CT image combine serum GM test can be considered as a val-uable tool to monitoring treatment effect in leukemia patient with IPA.关键词
白血病/GM 实验/曲霉菌病/CTKey words
leukemia/galactomannan/invasive pulmonary aspergillosis/CT分类
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李明,李功杰,周娟,盛复庚,乔鹏岗..肺部 CT 联合血清半乳甘露聚糖实验在白血病并发侵袭性肺曲霉菌病诊断及疗效评价中的应用[J].中国真菌学杂志,2016,11(1):20-23,27,5.