中国真菌学杂志2016，Vol.11Issue(1)：48-50,3.
1%卢立康唑乳膏治疗足癣的疗效和安全性评价
Evaluation of efficacy and safety of 1% luliconazole cream in the treatment of tinea pedis
张静 1蔡文莹 1肖星 1马坚池 1席丽艳1
作者信息
- 1. 中山大学孙逸仙纪念医院皮肤性病科，广州 510120
- 折叠
摘要
Abstract
Objective To compare the efficacy and safety of 1% luliconazole cream and 1% terbinafine hydrochloride cream in the treatment of tinea pedis.Methods A single-center,single-blind,randomized controlled trial was conducted.1% lulicon-azole cream was applied in the trial group once daily for 2 weeks and 1% terbinafine hydrochloride cream in control group was applied twice daily for 2 weeks.Patients were evaluated at 0 (baseline),2,4 weeks.Results Thirty cases in the trial group and 30 cases in control group were evaluated.The clinical effective rate at 2 weeks was 63.33% in the trial group and 76.67% in control group;and 93.33% versus 90.00% at 4 weeks respectively.Mycological cure rates at 2 weeks and 4 weeks were 46.67% and 86.67% in the trial group,and in control group they were 53.33% and 80.00% respectively.The total effec-tive rate at week 2 was 43.33% in the trial group and 60.00% in control group;and 86.67% versus 80.00% at 4 weeks,re-spectively.Treatment-related adverse events consisted of local irritation,occurred in 3.33% of patients both in the trial group and control group.The efficacy and safety of 1% luliconazole cream in the treatment of tinea pedis are similar to that of 1%terbinafine hydrochloride cream (P >0.05 ).Conclusion This study suggests that 1% luliconazole cream was effective and safe in the treatment of tinea pedis.关键词
卢立康唑/特比萘芬/足癣Key words
luliconazole/terbinafine/tinea pedis分类
医药卫生引用本文复制引用
张静,蔡文莹,肖星,马坚池,席丽艳..1%卢立康唑乳膏治疗足癣的疗效和安全性评价[J].中国真菌学杂志,2016,11(1):48-50,3.
