中国卒中杂志2016，Vol.11Issue(3)：179-183,5.DOI:10.3969/j.issn.1673-5765.2016.03.004
可逆性后部白质脑病综合征的临床和影像学特点
Clinical and Imaging Characteristics of Reversible Posterior Leukoencephalopathy Syndrome
刘丽 1吴铮 1杜娟 1段文博 1李敏 2张妍 3陈志明 4蔡艺灵1
作者信息
- 1. 11000101 北京中国人民解放军第306医院神经内科
- 2. 中国人民解放军第306医院磁共振室
- 3. 中国人民解放军第306医院妇产科
- 4. 中国人民解放军第306医院骨科
- 折叠
摘要
Abstract
Objective To investigate the clinical and imaging characteristics of reversible posterior leukoencephalopathy syndrome (RPLES). Methods The clinical manifestation and imaging finding of 4 patients were analyzed retrospectively. Results The cause of those enrolled subjects included renal failure, hypertension, eclampsia gravidarum and post-operation of lumbar surgery. All 4 cases had the clinical manifestations of headache and epilepsy, nausea and vomiting and mental behavior disorder. Among which, there were 1 case of acroparalysis, 1 case of aphasia and 1 case of persistent state of epilepsy. magnetic resonance imaging (MRI) showed bilateral or unilateral leukoencephalopathy and grey matter lesion in parieto-occipital subcortical lobes, and the lesion area might involve frontal-temple lobe. The MRI apparent diffusion coefifcient (ADC), T2 weighted image, scan lfuid attenuated inversion recovery (FLAIR) sequence were all presenting hyperintense and T1 weighted image were presenting slightly hyperintense. MRI susceptibility weighted imaging showed micro-bleeding in 1 case. Conclusion RPLES is associated with miscellaneous causes. Epilepsy and headache are the principal clinical symptoms in RPLES. Imageological changes are mainly cortical and subcortical edema.关键词
可逆性后部白质脑病综合征/磁共振成像/癫痫Key words
Reversible posterior leukoencephalopathy syndrome/Magnetic resonance imaging/Epilepsy引用本文复制引用
刘丽,吴铮,杜娟,段文博,李敏,张妍,陈志明,蔡艺灵..可逆性后部白质脑病综合征的临床和影像学特点[J].中国卒中杂志,2016,11(3):179-183,5.
