动物营养学报2016，Vol.28Issue(3)：695-703,9.DOI:10.3969/j.issn.1006-267x.2016.03.009
肥胖影响呼吸系统抗感染的机制
Mechanisms of Impact of Obesity on Respiratory Infection
万涛梅 1甘霖莉 1左之才 1任毅1
作者信息
- 1. 四川农业大学动物医学院，环境公害与动物疾病四川省高校重点实验室，动物疫病与人类健康四川省重点实验室，雅安 625014
- 折叠
摘要
Abstract
Obesity is a chronic metabolic disease caused by many factors, and it is also a kind of systemic low grade inflammation, which affects both the energy metabolism and immune state in the body.A large numbers of studies have reported that obesity has a certain effect on the function of respiratory system, which not only improves the severity of respiratory diseases, increases the risk of respiratory tract infections, also destroys the capacity to clear the pathogens.Even though, there are some voices said that obesity is associated with lower odds and hospital mortality, but the specific mechanism is still unknown.It is clear that the increased inflamma-tory cells infiltration and the elevated inflammatory mediators and adipocytokines caused by the substantial ac-cumulation of adipose tissue in obese individuals may be the main factors contributing to the alters of lung sus-ceptibility to pathogenic microorganisms.This review summarizes the mechanisms of obesity may affect respira-tory resistance to infections, to lay a certain foundation for further exploring the relationship between obesity and lung infection.关键词
肥胖/呼吸道/感染/机制Key words
obesity/respiratory tract/infection/mechanism分类
农业科技引用本文复制引用
万涛梅,甘霖莉,左之才,任毅..肥胖影响呼吸系统抗感染的机制[J].动物营养学报,2016,28(3):695-703,9.
