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结核性脑膜炎患者应用脑脊液置换联合鞘内注药的临床疗效研究

陈新灿

国际医药卫生导报2016,Vol.22Issue(6):798-801,4.
国际医药卫生导报2016,Vol.22Issue(6):798-801,4.DOI:10.3760/cma.j.issn.1007-1245.2016.06.020

结核性脑膜炎患者应用脑脊液置换联合鞘内注药的临床疗效研究

Cerebrospinal fluid replacement combined with intrathecal drug injection for patients with tuberculous meningitis

陈新灿1

作者信息

  • 1. 251700 滨州市中心医院结防院结核三科
  • 折叠

摘要

Abstract

Objective To evaluate the clinical efficacy of cerebrospinal fluid replacement combined with intrathecal drug injection for patients with tuberculous meningitis.Methods 91 patients with tuberculous meningitis were selected as study objects and randomly divided into a control group (n=45),treated with conventional anti-TB treatment,and an observation group (n=46),treated with cerebrospinal fluid replacement and intrathecal drug injection.The clinical efficacies were compared between these two groups.Results After the treatment,the total efficacy was 95.7% in the observation group,which was significantly higher than that in the control group,with a statistical difference (P<0.05).The indicators of cerebrospinal fluid and symptomrelief time were better in the observation group than in the control group,with statistical differences(P<0.05).No significant adverse reactions occurred in both groups.Conclusions Cerebrospinal fluid replacement combined with intrathecal drug injection for patients with tuberculous meningitis can promote the recovery of their cerebrospinal fluid indicators and effectively improve their prognosis and is worth for clinical application.

关键词

脑脊液置换/鞘内注药/结核性脑膜炎/临床疗效

Key words

Cerebrospinal fluid replacement/Intrathecal drug injection/Tuberculous meningitis/Clinical efficacy

引用本文复制引用

陈新灿..结核性脑膜炎患者应用脑脊液置换联合鞘内注药的临床疗效研究[J].国际医药卫生导报,2016,22(6):798-801,4.

国际医药卫生导报

1007-1245

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