临床口腔医学杂志2016，Vol.32Issue(2)：67-69,3.DOI:10.3969/j.issn.1003-1634.2016.02.002
骨诱导活性材料复合富血小板纤维蛋白在拔牙位点引导新骨形成的骨计量学研究
Osteoinductive active material complex with Platelet-rich fibrin guide the new bone formation on extraction sites by bone histomorphometry
摘要
Abstract
Objective:The aim of the study was to explore study the effect that osteoinductive active material(OAM) combined with platelet-rich fibrin (PRF) lead to the formation of new bone in the extraction site,and to investigate the re-sult that the composite promoted the preservation and restoration of extraction site. Method:The 12-month-old male Beagle dogs with the number of six were extracted both second maxillary and mandibular lateral incisors with the minimally extract-ed method. To establish the animal model,the four sites were randomly divided into four groups,as A,B,C and D. The for-mer three groups were filled with OAM-PRF composite,OAM and PRF respectively,and D controlled group. Three dogs were randomly sacrificed after one-month treatment,and the left three dogs were sacrificed after three-month treatment. The samples were taken from the alveolar bone and as followed stained with toluidine blue and H.E respectively for histomorpho-metric observation. Result:The trabecular width,trabeculae area and an osteoblastic number of group A are significantly higher than the other three groups(P<0.01). The factorial analysis shows the effect of the OAM-PRF complex is superior to use OAM or PRF alone,guiding the new bone formation in the extraction site area. Conclusion:The number of osteoblasts can increase significantly under the effect of OMA complex with PRF,which contribute to bone remodeling and improving the quality of alveolar bone in tooth extraction site.关键词
骨诱导活性材料/富血小板纤维蛋白/拔牙位点/新骨形成/骨计量学Key words
Osteoinduction Active Material/Platelet-rich Fibrin/Extraction Site/New Bone Formation/Bone Histo-morphometry分类
医药卫生引用本文复制引用
周春梅,温齐古丽·乃库力,于莉,袁萍,尼加提·吐尔逊..骨诱导活性材料复合富血小板纤维蛋白在拔牙位点引导新骨形成的骨计量学研究[J].临床口腔医学杂志,2016,32(2):67-69,3.基金项目
新疆维吾尔自治区自然科学基金 （）
