陕西中医2016，Vol.37Issue(4)：396-397,2.DOI:10.3969/j.issn.1000-7369.2016.04.005
黄芪桂枝五物汤加减对卵巢癌 TP方案化疗引起神经毒性的防治效果
Control effect of Huangqi Guizhi Wuwu decoction on neurotoxicity which caused by TP chemotherapy regimen of ovarian cancer
摘要
Abstract
Objective:To investigate the preventive and therapeutic effect of Huangqi Guizhi Wuwu decoction on neurotoxicity which caused by TP chemotherapy regimen of ovarian cancer .Methods :76 patients with ovarian cancer who were introduced with TP chemotherapy regimen in our hospital from March 2012 to October 2014 were selected as the research object and randomly divided into control group (38 cases) and observation group (38 cases) .Neurotoxicity was treated with Mecobalamin tablets and Huangqi Guizhi Wuwu decoction respectively ,and the changes of each index were analyzed after treatment .Results:The observation group’s incidence of neurotoxicity after 6 cycles was 34 .21% , and that of the control group was 63 .16% ,and the grade of neurotoxicity in observation group was lower than that in the control group ;the difference was statistically significant (P<0 .05);the nerve conduction velocity before chemotherapy in the two groups has no significant difference ,after 6 cycles'chemotherapy ,the changes of nerve conduction velocity in observation group was lower than that in the control group (P<0 .05) .Conclusion :It is effective to use Huangqiguizhi Wuwu decoction to treat neurotoxicity which caused by TP chemotherapy regimen of ovarian cancer ,and it can reduce the incidence of neurotoxicity ,protect the nerve conduction velocity ,therefore it is worthy of application .关键词
卵巢肿瘤/中西医结合疗法/补气剂/治疗应用/黄芪桂枝五物汤Key words
Ovariancancer/intergrative therapy/Qi-Reinforcingagents/therapeuticuses/Huangqi Guizhi Wuwu decoction分类
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徐先容..黄芪桂枝五物汤加减对卵巢癌 TP方案化疗引起神经毒性的防治效果[J].陕西中医,2016,37(4):396-397,2.基金项目
湖北省科技厅项目 （）
