山西医科大学学报2016，Vol.47Issue(3)：289-292,293,5.DOI:10.13753/j.issn.1007-6611.2016.03.021
18 F-FDG PET/CT显像对直肠癌术后骶前复发的诊断价值
Diagnostic value of 18 F-FDG PET/CT for presacral recurrence in patients with rectal cancer
摘要
Abstract
Objective To assess the value of 18 F-FDG PET/CT in the diagnosis of presacral recurrence after Mile’ s operation for rec-tal cancer patients. Methods Sixty-one patients with presacral lesions after operation for rectal cancer underwent 18 F-FDG PET/CT. The images were interpreted by visual and semi-quantitative analysis(maximum standard uptake value, SUVmax). All the cases were confirmed by pathology and clinical follow up( >6 months) . The sensitivity, specificity of 18 F-FDG PET/CT for detecting presacral re-currence were calculated. Results Thirty cases were confirmed presacral recurrence of rectal cancer, and 31 cases were diagnosed as benign diseases. SUVmax was 9. 44 ± 3. 78 for recurrence lesions and 2. 24 ± 2. 15 for benign lesions. The uptake of 18 F-FDG was significantly higher in presacral recurrence lesions than in benign lesions(t=9. 10,P<0. 01). ROC curve analysis showed that a cut-off value of SUVmax was 4. 45 for benign and malignant lesions. The sensitivity of 18 F-FDG PET/CT was 96%, and the specificity was 87%. The area under the ROC curve was 0. 976. Conclusion The uptake of 18 F-FDG in presacral recurrent lesions is higher than that in benign lesions. The cut-off value of SUVmax is 4. 45 for malignant and benign lesions. 18 F-FDG PET/CT in the diagnosis of pre-sacral recurrence after operation for rectal cancer have a good diagnostic value.关键词
直肠癌/骶前复发/正电子发射断层显像术/CTKey words
rectal cancer/presacral recurrence/positron emission-tomography/CT分类
医药卫生引用本文复制引用
李雪娜,李娜,杜补林,李亚明..18 F-FDG PET/CT显像对直肠癌术后骶前复发的诊断价值[J].山西医科大学学报,2016,47(3):289-292,293,5.基金项目
辽宁省科学技术计划基金资助项目(2010225032) （2010225032）
辽宁省科学技术计划基金资助项目(2012225013) （2012225013）
